Post-COVID-19 syndrome and humoral response association after 1 year in vaccinated and unvaccinated patients.

ABSTRACT:

Objectives

This study aimed to describe the impact of vaccination and the role of humoral responses on post-COVID-19 syndrome 1 year after the onset of SARS coronavirus type 2 (CoV-2).

Methods

This prospective study was conducted through interviews to investigate post-COVID-19 syndrome 6 and 12 months after disease onset in all adult in- and outpatients with COVID-19 at Udine Hospital (March-May 2020). Vaccination status and two different serological assays to distinguish between response to vaccination (receptor-binding domain (RBD) SARS-CoV-2 IgG) and/or natural infection (non-RBD-SARS-CoV-2 IgG) were also assessed.

Results

A total of 479 patients (52.6% female; mean age: 53 years) were interviewed 13.5 months (standard deviation: 0.6 months) after acute infection.

SUBMITTER: Peghin M 

PROVIDER: S-EPMC8940723 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature