Metabolomics-based profiling of 4 avocado varieties using HPLC-MS/MS and GC/MS and evaluation of their antidiabetic activity.

ABSTRACT: Seven avocado "Persea americana" seeds belonging to 4 varieties, collected from different localities across the world, were profiled using HPLC-MS/MS and GC/MS to explore the metabolic makeup variabilities and antidiabetic potential. For the first time, 51 metabolites were tentatively-identified via HPLC-MS/MS, belonging to different classes including flavonoids, biflavonoids, naphthodianthrones, dihydrochalcones, phloroglucinols and phenolic acids while 68 un-saponified and 26 saponified compounds were identified by GC/MS analysis. The primary metabolic variabilities existing among the different varieties were revealed via GC/MS-based metabolomics assisted by unsupervised pattern recognition methods. Fatty acid accumulations were proved as competent, and varietal-discriminatory metabolite

SUBMITTER: Younis IY 

PROVIDER: S-EPMC8943142 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature