Prognostic significance of mean platelet volume in patients with lung cancer: a meta-analysis.

ABSTRACT:

Objective

The mean platelet volume (MPV) is a measure of platelet size, and it is considered a surrogate marker of platelet activation. Because the correlation between platelet count/size and lung cancer prognosis remains unclear, this meta-analysis comprehensively evaluated the prognostic significance of MPV among patients with lung cancer.

Methods

A systematic search of PubMed, Embase, Google Scholar, and additional sources of relevant studies were conducted with no language restrictions from inception to 7 May 2021. Overall survival (OS) and disease-free survival (DFS)/progression-free survival (PFS), as well as their hazard ratios (HR) and 95% confidence intervals (CIs), were pooled to evaluate the relationship between MPV and survival. The study protocol was registered

SUBMITTER: Kharel S 

PROVIDER: S-EPMC8943633 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature