Copy number variation of the CCDC39 gene is associated with growth traits in Chinese cattle.

ABSTRACT:

Background

Copy number variation (CNV) has become an essential part of genetic structural variation. Coiled-coil domain containing 39 (CCDC39) is a gene that related to the growth and development of organs and tissues. It is identified that it has a CNV region by animal genome resequencing.

Objective

In this study, we detected the phenotypic traits and different distributions of CCDC39 gene copy numbers in five Chinese cattle breeds (Qinchuan (QC) cattle, Yunling (YL) cattle, Xianan (XN) cattle, Pinan (PN) cattle and Jiaxian (JX) cattle).

Methods

Five hundred and six cattle were randomly selected for CNV distribution detection. Blood samples were taken and genomic DNA was extracted. Different tissues were obtained from adult (n = 3) XN cattle, including heart, liver,

SUBMITTER: Hu L 

PROVIDER: S-EPMC8959325 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature