Use of Impella device in cardiogenic shock and its clinical outcomes: A systematic review and meta-analysis.

ABSTRACT:

Introduction

Cardiogenic shock (CS) is a life-threatening condition and mechanical circulatory support (MCS) might exert a relevant impact on its clinical course. Among MCS devices, Impella is very promising. Yet, its usefulness is still debated. We performed a meta-analysis of all studies evaluating the clinical impact of Impella in CS.

Methods

All studies including patients with CS and treated with Impella were included. The primary endpoint was short-term mortality. Secondary endpoints were vascular access complications and major bleeding. Data synthesis was obtained using random-effects metanalysis.

Results

Thirty-three studies and 5204 patients were included. Short-term mortality was 47%. Meta-regression analysis showed that patients age (p = 0.01), higher suppor

SUBMITTER: Panuccio G 

PROVIDER: S-EPMC8961185 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature