Aerobic Methoxydotrophy: Growth on Methoxylated Aromatic Compounds by Methylobacteriaceae.

ABSTRACT: Pink-pigmented facultative methylotrophs have long been studied for their ability to grow on reduced single-carbon (C₁) compounds. The C₁ groups that support methylotrophic growth may come from a variety of sources. Here, we describe a group of Methylobacterium strains that can engage in methoxydotrophy: they can metabolize the methoxy groups from several aromatic compounds that are commonly the product of lignin depolymerization. Furthermore, these organisms can utilize the full aromatic ring as a growth substrate, a phenotype that has rarely been described in Methylobacterium. We demonstrated growth on p-hydroxybenzoate, protocatechuate, vanillate, and ferulate in laboratory culture conditions. We also used comparative genomics to explore the ev

SUBMITTER: Lee JA 

PROVIDER: S-EPMC8963497 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature