Associations between depressive symptoms and disease progression in older patients with chronic kidney disease: results of the EQUAL study.

ABSTRACT:

Background

Depressive symptoms are associated with adverse clinical outcomes in patients with end-stage kidney disease; however, few small studies have examined this association in patients with earlier phases of chronic kidney disease (CKD). We studied associations between baseline depressive symptoms and clinical outcomes in older patients with advanced CKD and examined whether these associations differed depending on sex.

Methods

CKD patients (≥65 years; estimated glomerular filtration rate ≤20 mL/min/1.73 m²) were included from a European multicentre prospective cohort between 2012 and 2019. Depressive symptoms were measured by the five-item Mental Health Inventory (cut-off ≤70; 0-100 scale). Cox proportional hazard analysis was used to study associations betw

SUBMITTER: Eveleens Maarse BC 

PROVIDER: S-EPMC8967670 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature