A Patient-Level Data Meta-analysis of the Abscopal Effect.

ABSTRACT:

Purpose

The abscopal effect is defined when a form of local therapy causes tumor regression of both the target lesion and any untreated tumors. Herein cases of the abscopal effect were systematically reviewed and a patient-level data analysis was performed for clinical predictors of both duration of response and survival.

Methods and materials

The Population, Intervention, Control, Outcome, Study (PICOS) design approach, Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) literature selection process, and Meta-analysis of Observational Studies in Epidemiology (MOOSE) were used to find articles published before September 2019 in MEDLINE/PubMed and Google Scholar. Inclusion criteria were (1) population: patients with reported abscopal response; (2) inte

SUBMITTER: Hatten SJ 

PROVIDER: S-EPMC8971834 | biostudies-literature | 2022 May-Jun

REPOSITORIES: biostudies-literature