Impact of mode of conception on early pregnancy human chorionic gonadotropin rise and birth weight.

ABSTRACT:

Objective

To assess whether the mode of conception and embryo biopsy impact first-trimester human chorionic gonadotropin (hCG) dynamics and subsequent risk of small for gestational age (SGA) or large for gestational age (LGA).

Design

Retrospective cohort study.

Setting

University fertility center.

Patients

Six hundred-two pregnant patients with singleton live births.

Interventions

Serial serum hCG measurements were obtained between 10 and 28 days postconception to determine the within-woman rate of change in hCG (slope) by mode of conception (unassisted pregnancy, fresh embryo transfer (ET), frozen ET, and frozen ET following preimplantation genetic testing for aneuploidy (PGT-A).

Main outcome measures

Primary outcomes included birth weight, SGA,

SUBMITTER: Richardson H 

PROVIDER: S-EPMC8978079 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature