CyberKnife versus multicatheter interstitial brachytherapy for accelerated partial breast irradiation: a dosimetrical assessment with focus on organs at risk.

ABSTRACT:

Background

The purpose of the study was to dosimetrically compare multicatheter interstitial brachytherapy (MIBT) and stereotactic radiotherapy with CyberKnife (CK) for accelerated partial breast irradiation with special focus on dose to organs at risk (OARs).

Materials and methods

Treatment plans of thirty-one patients treated with MIBT were selected and additional CK plans were created on the same CT images. The OARs included ipsilateral non-target and contralateral breast, ipsilateral and contralateral lung, skin, ribs, and heart for left sided cases. The fractionation was identical (4 × 6.25 Gy). Dose-volume parameters were calculated for both techniques and compared.

Results

The D90 of the PTV for MIBT and CK were similar (102.4% vs. 103.6%, p = 0.0

SUBMITTER: Herein A 

PROVIDER: S-EPMC8989445 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature