Hepatitis B virus infection and factors associated with its acquisition among adults in a Lake Victoria HIV hyperendemic fishing community in Kyotera district, Uganda: a cross-sectional observation.

ABSTRACT:

Objective

To investigate hepatitis B virus (HBV) prevalence and factors associated with viral acquisition in a HIV-hyperendemic fishing community, we tested sera for anti-hepatitis B core (HBc) and hepatitis B surface antigen (HBsAg).

Design

Observational cross-sectional study.

Setting

Large fishing village on Lake Victoria, one of the HIV-hyperendemic Rakai Community Cohort Study (RCCS) sites (HIV prevalence ~40%).

Participants

Sample of 460 RCCS participants aged 15-49 years from survey conducted from 5 December 2016 to 13 February 2017. These proportionately included HIV-negative, HIV-positive antiretroviral therapy (ART)-naïve and HIV positive on ART participants.

Results

Of the 460 participants, 49.6% (95% CI 45.0% to 54.1%) had evidence of prior HB

SUBMITTER: Ssuuna C 

PROVIDER: S-EPMC8990708 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature