Glial changes in schizophrenia: Genetic and epigenetic approach.

ABSTRACT:

Background

Schizophrenia (SCZ) is a severe mental illness that affects one percent of the population, affecting how people think, feel, and behave. Evidence suggests glial cell alteration and some researchers have found genetic risk loci and epigenetic marks that may regulate glia-related genes implicated in SCZ.

Aim

The aim of this study is to identify genetic and epigenetic changes that have been reported in glial cells or glial-associated genes in SCZ.

Materials and methods

We searched the articles from PubMed, PubMed Central, Medline, Medscape, and Embase databases up to December 2020 to identify relevant peer-reviewed articles in English. The titles and abstracts were screened to eliminate irrelevant citations.

Results

Twenty-four original articles were in

SUBMITTER: Francisco RD 

PROVIDER: S-EPMC8992743 | biostudies-literature | 2022 Jan-Feb

REPOSITORIES: biostudies-literature