Ontology highlight
ABSTRACT:
SUBMITTER: Solyman MSM
PROVIDER: S-EPMC8999750 | biostudies-literature | 2022 Apr
REPOSITORIES: biostudies-literature
Solyman Muna Salem M MSM Ujczo Jessica J Brayton Kelly A KA Shaw Dana K DK Schneider David A DA Noh Susan M SM
International journal of molecular sciences 20220401 7
<i>Anaplasma</i> spp. are obligate intracellular, tick-borne, bacterial pathogens that cause bovine and human anaplasmosis. We lack tools to prevent these diseases in part due to major knowledge gaps in our fundamental understanding of the tick-pathogen interface, including the requirement for and molecules involved in iron transport during tick colonization. We determine that iron is required for the pathogen <i>Anaplasma marginale</i>, which causes bovine anaplasmosis, to replicate in <i>Derma ...[more]