Early stage ovarian immature teratoma, surveillance or chemotherapy after surgery? A propensity score matched analysis.

ABSTRACT:

Objective

To compare the survival outcomes between surveillance and adjuvant chemotherapy in patients with stage I ovarian immature teratomas (ITs) who underwent fertility sparing surgery.

Methods

In this retrospective cohort analysis, patients with stage IA Grade 2-3, stage IB and IC ovarian ITs who underwent surveillance after surgery between 2016 and 2021 from Peking Union Medical College Hospital were identified. A 1:1 propensity score matching was performed in patients who had adjuvant chemotherapy by age, stage, and grade.

Results

A total of 16 patients without adjuvant chemotherapy were identified. There were 3 stage IA and 13 stage IC patients. The median age at diagnosis was 14.5 years old (range 3-30). There were 6 patients who had grade 1 tumor, 5 grade 2,

SUBMITTER: Zhang X 

PROVIDER: S-EPMC9011035 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature