Cannabis Use Is Associated With Lower COVID-19 Susceptibility but Poorer Survival.

ABSTRACT:

Objectives

To investigate the impact of cannabis use on the infection and survival outcomes of COVID-19.

Study design

Cross-sectional study based on the UK Biobank (UKB) dataset.

Methods

We identified 13,099 individuals with cannabis smoking history in the UKB COVID-19 Serology Study. The Charlson-Quan Comorbidity Index was estimated using inpatient ICD-10 records. Multivariable logistic regression characterized features associated with COVID-19 infection. Cox models determined the hazard ratios (HR) for COVID-19-related survival.

Results

Cannabis users were more likely to getting COVID-19 (odds ratio: 1.22, P = 0.001) but multivariable analysis showed that cannabis use was a protective factor of COVID-19 infection (adjusted odds ratio: 0.81, P =

SUBMITTER: Huang D 

PROVIDER: S-EPMC9012397 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature