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ABSTRACT: Significance
Current open-source Monte Carlo (MC) method implementations for light propagation modeling are many times tedious to build and require third-party licensed software that can often discourage prospective researchers in the biomedical optics community from fully utilizing the light propagation tools. Furthermore, the same drawback also limits rigorous cross-validation of physical quantities estimated by various MC codes.Aim
Proposal of an open-source tool for light propagation modeling and an easily accessible dataset to encourage fruitful communications amongst researchers and pave the way to a more consistent comparison between the available implementations of the MC method.Approach
The PyXOpto implementation of the MC method for multilayered and voxelated tissues based on the Python programming language and PyOpenCL extension enables massively parallel computation on numerous OpenCL-enabled devices. The proposed implementation is used to compute a large dataset of reflectance, transmittance, energy deposition, and sampling volume for various source, detector, and tissue configurations.Results
The proposed PyXOpto agrees well with the original MC implementation. However, further validation reveals a noticeable bias introduced by the random number generator used in the original MC implementation.Conclusions
Establishing a common dataset is highly important for the validation of existing and development of MC codes for light propagation in turbid media.
SUBMITTER: Burmen M
PROVIDER: S-EPMC9016074 | biostudies-literature | 2022 Apr
REPOSITORIES: biostudies-literature

Bürmen Miran M Pernuš Franjo F Naglič Peter P
Journal of biomedical optics 20220401 8
<h4>Significance</h4>Current open-source Monte Carlo (MC) method implementations for light propagation modeling are many times tedious to build and require third-party licensed software that can often discourage prospective researchers in the biomedical optics community from fully utilizing the light propagation tools. Furthermore, the same drawback also limits rigorous cross-validation of physical quantities estimated by various MC codes.<h4>Aim</h4>Proposal of an open-source tool for light pro ...[more]