An Updated Overview of MRI Injuries in Neonatal Encephalopathy: LyTONEPAL Cohort.

ABSTRACT:

Background

Brain magnetic resonance imaging (MRI) is a key tool for the prognostication of encephalic newborns in the context of hypoxic-ischemic events. The purpose of this study was to finely characterize brain injuries in this context.

Methods

We provided a complete, descriptive analysis of the brain MRIs of infants included in the French national, multicentric cohort LyTONEPAL.

Results

Among 794 eligible infants, 520 (65.5%) with MRI before 12 days of life, grade II or III encephalopathy and gestational age ≥36 weeks were included. Half of the population had a brain injury (52.4%); MRIs were acquired before 6 days of life among 247 (47.5%) newborns. The basal ganglia (BGT), white matter (WM) and cortex were the three predominant sites of injuries, affecting 33.8%

SUBMITTER: Beck J 

PROVIDER: S-EPMC9032533 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature