Dataset Information

Cardiovascular Health at Age 5 Years: Distribution, Determinants, and Association With Neurodevelopment.

ABSTRACT:

Background

Early childhood may represent an opportune time to commence primordial prevention of cardiovascular disease (CVD, i.e., prevention of risk factors onset), but epidemiological evidence is scarce. We aimed to examine the distribution and parental and early life determinants of ideal cardiovascular health (CVH) in children up to 5 years and to compare the level of cognitive development between children with and without ideal CVH at age 5 years.

Methods

Using data from the Etude sur les déterminants pré et post natals précoces du Développement psychomoteur et de la santé de l'Enfant (EDEN) study, a French population-based mother-child cohort study, CVH was examined in children at 5 years of age based on the American Heart Association CVH metrics (ideal body mass index, physical activity, diet, blood pressure, cholesterol and glucose levels, and passive smoking, considered in sensitivity analysis only). Children were categorized as having ideal (five to six ideal metrics) or non-ideal CVH (<5 ideal metrics). Intelligence quotient (IQ) at age 5 years was assessed using the French version of the Wechsler Preschool and Primary Scale of Intelligence.

Results

Among the 566 children (55% boys), only 34% had ideal CVH. In fully adjusted logistic regression, boys compared to girls (OR = 1.77, 95% CI 1.13-2.78), children with intermediate (1.77, 1.05-2.98) or ideal (2.58, 1.38-4.82) behavioral CVH at age 3 years and children who spent < 30 min/day watching television (1.91, 1.09-3.34) at age 3 years were more likely to have ideal CVH at age 5 years. At age 5 years, there was a significant 2.98-point difference (95% CI 0.64-5.32) in IQ between children with and without ideal biological CVH after adjusting for confounders.

Conclusion

This study highlights that only a third of children aged 5 years had ideal CVH and identified modifiable determinants of ideal CVH and is suggestive of an association between CVH and neurodevelopment at a young age.

SUBMITTER: Climie RE

PROVIDER: S-EPMC9035843 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature

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Publications

Cardiovascular Health at Age 5 Years: Distribution, Determinants, and Association With Neurodevelopment.

Climie Rachel E RE Tafflet Muriel M van Sloten Thomas T de Lauzon-Guillain Blandine B Bernard Jonathan Y JY Dargent-Molina Patricia P Plancoulaine Sabine S Lioret Sandrine S Jouven Xavier X Charles Marie-Alines MA Heude Barbara B Empana Jean-Philippe JP

Frontiers in pediatrics 20220411

<h4>Background</h4>Early childhood may represent an opportune time to commence primordial prevention of cardiovascular disease (CVD, i.e., prevention of risk factors onset), but epidemiological evidence is scarce. We aimed to examine the distribution and parental and early life determinants of ideal cardiovascular health (CVH) in children up to 5 years and to compare the level of cognitive development between children with and without ideal CVH at age 5 years.<h4>Methods</h4>Using data from the ...[more]

PMID: 35479759

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Dataset Information

Cardiovascular Health at Age 5 Years: Distribution, Determinants, and Association With Neurodevelopment.

Background

Methods

Results

Conclusion

Publications

Cardiovascular Health at Age 5 Years: Distribution, Determinants, and Association With Neurodevelopment.

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