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One pot synthesis of aryl nitriles from aromatic aldehydes in a water environment.

ABSTRACT: In this study, we found a green method to obtain aryl nitriles from aromatic aldehyde in water. This simple process was modified from a conventional method. Compared with those approaches, we used water as the solvent instead of harmful chemical reagents. In this one-pot conversion, we got twenty-five aryl nitriles conveniently with pollution to the environment being minimized. Furthermore, we confirmed the reaction mechanism by capturing the intermediates, aldoximes.

SUBMITTER: Lin H 

PROVIDER: S-EPMC9036638 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature

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One pot synthesis of aryl nitriles from aromatic aldehydes in a water environment.

Lin Hongyan H   Zhou Ziling Z   Ma Xiaopeng X   Chen Qingqing Q   Han Hongwei H   Wang Xiaoming X   Qi Jinliang J   Yang Yonghua Y  

RSC advances 20210709 39

In this study, we found a green method to obtain aryl nitriles from aromatic aldehyde in water. This simple process was modified from a conventional method. Compared with those approaches, we used water as the solvent instead of harmful chemical reagents. In this one-pot conversion, we got twenty-five aryl nitriles conveniently with pollution to the environment being minimized. Furthermore, we confirmed the reaction mechanism by capturing the intermediates, aldoximes. ...[more]

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