Current and emerging treatment modalities for spinocerebellar ataxias.

ABSTRACT:

Introduction

Spinocerebellar ataxias (SCA) are a group of rare neurodegenerative diseases that dramatically affect the lives of affected individuals and their families. Despite having a clear understanding of SCA's etiology, there are no current symptomatic or neuroprotective treatments approved by the FDA.

Areas covered

Research efforts have greatly expanded the possibilities for potential treatments, including both pharmacological and non-pharmacological interventions. Great attention is also being given to novel therapeutics based in gene therapy, neurostimulation, and molecular targeting. This review article will address the current advances in the treatment of SCA and what potential interventions are on the horizon.

Expert opinion

SCA is a highly complex and mult

SUBMITTER: Ghanekar SD 

PROVIDER: S-EPMC9048095 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature