Physicochemical and structural properties of lidocaine-based ionic liquids with anti-inflammatory anions.

ABSTRACT: The purpose of this paper was to examine the density, viscosity and electrical conductivity at different temperatures, as well as the thermal stability and structural properties of previously reported ionic liquids based on active pharmaceutical ingredients. Lidocaine-based ionic liquids, with ibuprofen and salicylate as counterion, were prepared first. Their structures were confirmed by infrared, mass and ¹H and ¹³C nuclear magnetic resonance spectroscopy. The Newtonian behaviour of lidocaine ibuprofenate was confirmed from viscosity measurement results, while it was impossible to determine for lidocaine salicylate. The interactions and structures of the studied ionic liquids were analyzed based on the measured density values, viscosity, electrical conductivity, and

SUBMITTER: Panic J 

PROVIDER: S-EPMC9051649 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature