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About the selectivity and reactivity of active nickel electrodes in C-C coupling reactions.

ABSTRACT: Active anodes which are operating in highly stable protic media such as 1,1,1,3,3,3-hexafluoroisopropanol are rare. Nickel forms, within this unique solvent, a non-sacrificial active anode at constant current conditions, which is superior to the reported powerful molybdenum system. The reactivity for dehydrogenative coupling reactions of this novel active anode increases when the electrolyte is not stirred during electrolysis. Besides the aryl-aryl coupling, a dehydrogenative arylation reaction of benzylic nitriles was found while stirring the mixture providing quick access to synthetically useful building blocks.

SUBMITTER: Beil SB

PROVIDER: S-EPMC9052091 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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About the selectivity and reactivity of active nickel electrodes in C-C coupling reactions.

Beil Sebastian B SB Breiner Manuel M Schulz Lara L Schüll Aaron A Müller Timo T Schollmeyer Dieter D Bomm Alexander A Holtkamp Michael M Karst Uwe U Schade Wolfgang W Waldvogel Siegfried R SR

RSC advances 20200408 24

Active anodes which are operating in highly stable protic media such as 1,1,1,3,3,3-hexafluoroisopropanol are rare. Nickel forms, within this unique solvent, a non-sacrificial active anode at constant current conditions, which is superior to the reported powerful molybdenum system. The reactivity for dehydrogenative coupling reactions of this novel active anode increases when the electrolyte is not stirred during electrolysis. Besides the aryl-aryl coupling, a dehydrogenative arylation reaction ...[more]

PMID: 35498499

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