Ontology highlight
ABSTRACT:
SUBMITTER: Pharaon RR
PROVIDER: S-EPMC9059780 | biostudies-literature | 2022 Apr
REPOSITORIES: biostudies-literature
Pharaon Rebecca R RR Gernon Thomas T Chang Sue S Vora Nayana N Villaflor Victoria M VM Bell Diana D Afkhami Michelle M Amini Arya A Sampath Sagus S Kang Robert R Maghami Ellie G EG Massarelli Erminia E
Cold Spring Harbor molecular case studies 20220428 3
Salivary gland tumors (SGTs) are heterogeneous tumors that range from benign masses to aggressive high-grade carcinomas with distant metastatic potential and limited response to chemotherapy. Mucoepidermoid carcinoma (MEC) accounts for 10% of SGTs and has a poor prognosis. In this research report, we describe two cases of metastatic high-grade MECs with prolonged response to immune checkpoint inhibitor pembrolizumab. Case 1 presented with a left neck mass, and biopsy of the parotid mass revealed ...[more]