Particle therapy using protons or carbon ions for cancer patients with cardiac implantable electronic devices (CIED): a retrospective multi-institutional study.

ABSTRACT:

Purpose

To evaluate the outcomes of particle therapy in cancer patients with cardiac implantable electronic devices (CIEDs).

Materials and methods

From April 2001 to March 2013, 19,585 patients were treated with proton beam therapy (PBT) or carbon ion therapy (CIT) at 8 institutions. Of these, 69 patients (0.4%, PBT 46, CIT 22, and PBT + CIT 1) with CIEDs (64 pacemakers, 4 implantable cardioverter defibrillators, and 1 with a cardiac resynchronization therapy defibrillator) were retrospectively reviewed. All the patients with CIEDs in this study were treated with the passive scattering type of particle beam therapy.

Results

Six (13%) of the 47 PBT patients, and none of the 23 CIT patients experienced CIED malfunctions (p = 0.105). Electrical resets (7) and over-sensin

SUBMITTER: Hashimoto T 

PROVIDER: S-EPMC9068656 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature