Ontology highlight
ABSTRACT:
SUBMITTER: Bast DJ
PROVIDER: S-EPMC90704 | biostudies-literature | 2001 Sep
REPOSITORIES: biostudies-literature
Antimicrobial agents and chemotherapy 20010901 9
Analysis of 71 ciprofloxacin-resistant (MIC > or = 4 microg/ml) Streptococcus pneumoniae clinical isolates revealed only 1 for which the quinolone resistance-determining regions of the parC, parE, and gyrB genes were genetically related to those of viridans group streptococci. Our findings support the occurrence of interspecies recombination of type II topoisomerase genes; however, its contribution to the emergence of quinolone resistance among pneumococci appears to have been minimal. ...[more]