Evaluation of imaging setups for quantitative phase contrast nanoCT of mineralized biomaterials.

ABSTRACT: X-ray nano-tomography with phase contrast (nanoCT) using synchrotron radiation is a powerful tool to non-destructively investigate 3D material properties at the nanoscale. In large bone lesions, such as severe bone fractures, bone cancer or other diseases, bone grafts substituting the lost bone might be necessary. Such grafts can be of biological origin or be composed of a synthetic bone substitute. The long-term functioning of artificial bone substitutes depends on many factors. Synchrotron nanoCT imaging has great potential to contribute to further the understanding of integration of implants into bone tissue by imaging the spatial interaction between bone tissue and implant, and by accessing the interface between implant material and bone tissue. With this aim, a methodology for evaluat

SUBMITTER: Suuronen JP 

PROVIDER: S-EPMC9070718 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature