Oxidative cyanation of N-aryltetrahydroisoquinoline induced by visible light for the synthesis of α-aminonitrile using potassium thiocyanate as a "CN" agent.

ABSTRACT: A novel method for the synthesis of α-aminonitrile through visible-light-induced oxidative cyanation of N-aryltetrahydroisoquinoline with potassium thiocyanate has been developed. The process does not require the use of a photocatalyst, transition metal reagent, strong oxidizing agent, or toxic cyano-containing compound, which makes the reaction simple and green.

SUBMITTER: Yi B 

PROVIDER: S-EPMC9071963 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature