β-Blocker Use and Cardiovascular Outcomes in Hemodialysis: A Systematic Review.

ABSTRACT:

Rationale & objective

There is conflicting evidence regarding the type of β-blockers to use in dialysis patients. This systematic review seeks to determine whether highly dialyzable β-blockers are associated with higher rates of cardiovascular events and mortality in hemodialysis patients than poorly dialyzable β-blockers.

Study design

A systematic review of the existing literature was conducted. A meta-analysis was performed using data from the selected studies.

Setting & study populations

Participants were from the United States, Canada, and Taiwan. The mean ages of participants ranged from 55.9-75.7 years.

Selection criteria for studies

We searched the Ovid MEDLINE database from 1990 to September 2020. Studies without adult hemodialysis participants and with

SUBMITTER: Tella A 

PROVIDER: S-EPMC9079357 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature