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A "Turn-On" fluorescent probe for sensitive and selective detection of fluoride ions based on aggregation-induced emission.

ABSTRACT: Based on the fluorophore of 2-(2'-hydroxyphenyl)benzothiazole (HBT) with aggregation-induced emission (AIE) properties, a highly selective and sensitive fluorescent probe PBT towards F^- was investigated. "Turn-On" fluorescence type signaling was realized by employing fluoride-selective cleavage of the latent thiophosphinated probe in mixed aqueous media. The probe is designed in such a way that the excited state intramolecular proton transfer (ESIPT) of the HBT moiety becomes blocked. The chemodosimetric approach of F^- to the probe results in the recovery of the ESIPT by removal of a free AIE-active HBT moiety through a subsequent hydrolysis process. The F^- detection limit of the probe was 3.8 nM in the dynamic range of 0.5 μM to 10 μM. In addition, the proposed probe has been used to detect F^- in water samples and toothpaste samples with satisfying results.

SUBMITTER: Du M

PROVIDER: S-EPMC9086254 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature

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A "Turn-On" fluorescent probe for sensitive and selective detection of fluoride ions based on aggregation-induced emission.

Du Man M Huo Baolong B Li Mengwen M Shen Ao A Bai Xue X Lai Yaru Y Liu Jiemin J Yang Yunxu Y

RSC advances 20180919 57

Based on the fluorophore of 2-(2'-hydroxyphenyl)benzothiazole (HBT) with aggregation-induced emission (AIE) properties, a highly selective and sensitive fluorescent probe PBT towards F<sup>-</sup> was investigated. "Turn-On" fluorescence type signaling was realized by employing fluoride-selective cleavage of the latent thiophosphinated probe in mixed aqueous media. The probe is designed in such a way that the excited state intramolecular proton transfer (ESIPT) of the HBT moiety becomes blocked. ...[more]

PMID: 35547726

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