The association between dietary patterns and the novel inflammatory markers platelet-activating factor and lipoprotein-associated phospholipase A2: a systematic review.

ABSTRACT:

Context

Atherosclerosis is a disease of chronic inflammation. Recent research has identified 2 novel inflammatory biomarkers: platelet-activating factor (PAF) and lipoprotein-associated phospholipase A2 (Lp-PLA2). Diet has been proposed as a mediator of inflammation, but to date, the focus for these novel biomarkers has been on individual foods and nutrients rather than overall dietary patterns.

Objective

To systematically review the literature on the association between dietary patterns and PAF and Lp-PLA2.

Data sources

The PubMed, Embase, CINAHL, and Cochrane CENTRAL literature databases were searched.

Data analysis

Study quality was evaluated using the Quality Criteria Checklist. Sixteen studies (n = 4 observational and n = 12 interventional) were included a

SUBMITTER: English CJ 

PROVIDER: S-EPMC9086773 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature