Apolipoprotein C-III in patients with systemic lupus erythematosus.

ABSTRACT:

Background

Systemic lupus erythematosus (SLE) has been associated with atherosclerotic cardiovascular disease (CV) and an altered lipid profile. High levels of apolipoprotein C-III (ApoC3) are associated with elevated triglyceride levels and an increased risk of CV. In the present study, we aimed to study circulating ApoC3 in patients with SLE and describe its relationship with the manifestations of the disease.

Methods

This is a cross-sectional study that included 186 patients with SLE. Disease-related data, CV comorbidity, full lipid profile, and serum levels of ApoC3 were assessed. A multivariable regression analysis was performed to study how ApoC3 was related to SLE features.

Results

Classic CV risk factors were significantly and strongly associated with circulat

SUBMITTER: Martin-Gonzalez C 

PROVIDER: S-EPMC9088095 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature