Long-term exposure to ambient air pollution and bladder cancer incidence in a pooled European cohort: the ELAPSE project.

ABSTRACT:

Background

The evidence linking ambient air pollution to bladder cancer is limited and mixed.

Methods

We assessed the associations of bladder cancer incidence with residential exposure to fine particles (PM_2.5), nitrogen dioxide (NO₂), black carbon (BC), warm season ozone (O₃) and eight PM_2.5 elemental components (copper, iron, potassium, nickel, sulfur, silicon, vanadium, and zinc) in a pooled cohort (N = 302,493). Exposures were primarily assessed based on 2010 measurements and back-extrapolated to the baseline years. We applied Cox proportional hazard models adjusting for individual- and area-level potential confounders.

Results

During an average of 18.2 years follow-up, 967 bladder cancer cases occurred. We observed a po

SUBMITTER: Chen J 

PROVIDER: S-EPMC9090745 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature