Long-Term Exposure to Source-Specific Fine Particles and Mortality─A Pooled Analysis of 14 European Cohorts within the ELAPSE Project.

ABSTRACT: We assessed mortality risks associated with source-specific fine particles (PM_2.5) in a pooled European cohort of 323,782 participants. Cox proportional hazard models were applied to estimate mortality hazard ratios (HRs) for source-specific PM_2.5 identified through a source apportionment analysis. Exposure to 2010 annual average concentrations of source-specific PM_2.5 components was assessed at baseline residential addresses. The source apportionment resulted in the identification of five sources: traffic, residual oil combustion, soil, biomass and agriculture, and industry. In single-source analysis, all identified sources were significantly positively associated with increased natural mortality risks. In multisource analysis, associations with all source

SUBMITTER: Chen J 

PROVIDER: S-EPMC9261290 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature