The role of children in household transmission of COVID-19: a systematic review and meta-analysis.

ABSTRACT:

Objectives

To explore household transmissibility of SARS-CoV-2 in children in new-variants dominating periods.

Methods

Through retrieval in PubMed and Embase, studies were included in two parts: meta-analysis of the household secondary attack rate (SAR) and case analysis of household pediatric infections.

Results

A total of 95 articles were included: 48 for meta-analysis and 47 for case analysis. Pediatric COVID-19 only comprised a minority of the household transmission. The total pooled household SAR of child index cases and contacts were 0.20 (95% confidence interval [CI]: 0.15-0.26) and 0.24 (95% CI: 0.18-0.30). Lower household transmissibility was reported in both child index cases and contacts than in adults (relative risk [RR] = 0.64, 95% CI: 0.50-0.81; RR = 0.7

SUBMITTER: Chen F 

PROVIDER: S-EPMC9091150 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature