Functional olfactory evolution in Drosophila suzukii and the subgenus Sophophora.

ABSTRACT: Comparative analyses of multiple genomes are used extensively to examine the gains and losses of chemosensory receptors across the genus Drosophila. However, few studies have delved into functional olfactory characteristics. Here we assess olfactory function across 20 species, and identify and describe several similar elements of evolution. We document (a) minor changes in functional ligands based on amino acid substitutions, (b) major changes in olfactory function or perhaps entire receptor replacements, and (c) that only a few receptors are subject to repeated changes, whereas 32 out of 37 OSNs are largely functionally conserved. In addition, we generate a robust model for identifying olfactory function using genomic data and comprehensive ligand-receptor combinations, which inclu

SUBMITTER: Keesey IW 

PROVIDER: S-EPMC9093017 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature