Vasodilatory Effect of Alpinia officinarum Extract in Rat Mesenteric Arteries.

ABSTRACT:

Background

Alpinia officinarum (A. officinarum) is known to exhibit a beneficial effect for anti-inflammatory, anti-oxidant, and anti-hyperlipidemic effects. However, no sufficient research data are available on the cardiovascular effect of A. officinarum. Thus, in this study, we investigate whether A. officinarum extract has direct effects on vascular reactivity.

Methods

To examine whether A. officinarum extract affects vascular functionality, we measured isometric tension in rat mesenteric resistance arteries using a wire myograph. After arteries were pre-contracted with high-K⁺ (70 mM), phenylephrine (5 µM), or U46619 (1 µM), A. officinarum extract was treated.

Results

A. officinarum extract induced vasodi

SUBMITTER: Haam CE 

PROVIDER: S-EPMC9104054 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature