Association of Operability With Post-Treatment Mortality in Early-Stage Non-Small Cell Lung Cancer.

ABSTRACT:

Background

Operability is both a crucial determinant in treatment selection and a potential confounder in analyses comparing surgery with non-surgical approaches such as stereotactic body radiotherapy (SBRT). We aimed to assess the association between operability status and intervention with post-treatment mortality in early-stage non-small cell lung cancer (NSCLC).

Patients and methods

We defined four groups of patients with cT1-T2N0M0 NSCLC diagnosed 2010 to 2014 from the National Cancer Database: SBRT patients deemed operable vs. inoperable and surgery patients receiving open vs. minimally-invasive approaches. Mortality rates at 30, 60, and 90 days post-treatment were calculated and compared.

Results

We abstracted 80,108 patients, 0.8% undergoing SBRT and operable,

SUBMITTER: Stokes WA 

PROVIDER: S-EPMC9106833 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature