Breast and thyroid cancer: A multicenter study with Accrual to Clinical Trials Network.

ABSTRACT:

Objective

To investigate a possible link between breast and thyroid cancer.

Methods

A multicenter retrospective review of patients in the electronic medical records of six Accrual to Clinical Trial (ACT) institutions with both breast cancer and thyroid carcinoma. Each center queried its data using a predefined data dictionary. Information on thyroid and breast cancer included dates of diagnosis, histology, and patient demographics.

Results

A random-effects model was used. There were 4.24 million women's records screened, 44 605 with breast cancer and 11 846 with thyroid cancer. The relative risks observed at each institution ranged from 0.49 to 13.47. The combined risk ratio (RR) estimate was 1.77 (95% confidence interval: 0.50-5.18).

Conclusion

There was no as

SUBMITTER: Peckham M 

PROVIDER: S-EPMC9106860 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature