DNA methylation may affect beef tenderness through signal transduction in Bos indicus.

ABSTRACT:

Background

Beef tenderness is a complex trait of economic importance for the beef industry. Understanding the epigenetic mechanisms underlying this trait may help improve the accuracy of breeding programs. However, little is known about epigenetic effects on Bos taurus muscle and their implications in tenderness, and no studies have been conducted in Bos indicus.

Results

Comparing methylation profile of Bos indicus skeletal muscle with contrasting beef tenderness at 14 days after slaughter, we identified differentially methylated cytosines and regions associated with this trait. Interestingly, muscle that became tender beef had higher levels of hypermethylation compared to the tough group. Enrichment analysis of predicted target genes suggested that differences in methylatio

SUBMITTER: de Souza MM 

PROVIDER: S-EPMC9107245 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature