Dementia Risk Score for a Population in Southern Europe Calculated Using Competing Risk Models.

ABSTRACT:

Background

Dementia prevention can be addressed if the intervention is applied early.

Objective

The objective of this study was to develop and validate competing risk models to predict the late risk of dementia based on variables assessed in middle age in a southern European population.

Methods

We conducted a prospective observational study of the EPIC-Spain cohort that included 25,015 participants. Dementia cases were identified from electronic health records and validated by neurologists. Data were gathered on sociodemographic characteristics and cardiovascular risk factors. To stratify dementia risk, Fine and Gray competing risk prediction models were constructed for the entire sample and for over-55-year-olds. Risk scores were calculated for low (the 30% of the sa

SUBMITTER: Ibarrondo O 

PROVIDER: S-EPMC9108562 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature