Association of Amygdala Development With Different Forms of Anxiety in Autism Spectrum Disorder.

ABSTRACT:

Background

The amygdala is widely implicated in both anxiety and autism spectrum disorder. However, no studies have investigated the relationship between co-occurring anxiety and longitudinal amygdala development in autism. Here, the authors characterize amygdala development across childhood in autistic children with and without traditional DSM forms of anxiety and anxieties distinctly related to autism.

Methods

Longitudinal magnetic resonance imaging scans were acquired at up to four time points for 71 autistic and 55 typically developing (TD) children (∼2.5-12 years, 411 time points). Traditional DSM anxiety and anxieties distinctly related to autism were assessed at study time 4 (∼8-12 years) using a diagnostic interview tailored to autism: the Anxiety Disorders Interview

SUBMITTER: Andrews DS 

PROVIDER: S-EPMC9116934 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature