Ontology highlight
ABSTRACT:
SUBMITTER: Peters BBC
PROVIDER: S-EPMC9121388 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20220505 19
Asymmetric hydrogenation of prochiral substrates such as ketones and olefins constitutes an important instrument for the construction of stereogenic centers, and a multitude of catalytic systems have been developed for this purpose. However, due to the different nature of the π-system, the hydrogenation of olefins and ketones is normally catalyzed by different metal complexes. Herein, a study on the effect of additives on the Ir-N,P-catalyzed hydrogenation of enones is described. The combination ...[more]