Effect of isoflavone supplementation on menopausal symptoms: a systematic review and meta-analysis of randomized controlled trials.

ABSTRACT:

Background/objectives

Complementary and alternative medicines can be used to alleviate climacteric symptoms that significantly affect the quality of life of postmenopausal women. Isoflavones are the most common plant-based therapies for postmenopausal changes, but the results of previous studies have been controversial.

Materials/methods

To investigate whether isoflavones would affect menopausal symptoms as well as ovarian hormones, we performed a systematic review and meta-analysis. The PubMed and EMBASE databases were used to perform the systematic search. Included studies were limited to randomized controlled trials (RCTs) assessing the impact of isoflavone supplementation on menopausal symptoms.

Results

Eleven studies were included for the final quantitative asses

SUBMITTER: Kang I 

PROVIDER: S-EPMC9127519 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature