Impact of COVID-19 Severity on Long-term Events in US Veterans using the Veterans Affairs Severity Index for COVID-19 (VASIC).

ABSTRACT: In this retrospective cohort study of 94,595 SARS-CoV-2 positive cases, we developed and validated an algorithm to assess the association between COVID-19 severity and long-term complications (stroke, myocardial infarction, pulmonary embolism/deep vein thrombosis, heart failure, and mortality). COVID-19 severity was associated with a greater risk of experiencing a long-term complication days 31-120 post-infection. Most incident events occurred days 31-60 post-infection and diminished after day 91, except heart failure for severe patients and death for moderate patients, which peaked days 91-120. Understanding the differential impact of COVID-19 severity on long-term events provide insight into possible intervention modalities and critical prevention strategies.

SUBMITTER: Galloway A 

PROVIDER: S-EPMC9129146 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature