Dataset Information

Usefulness of Bacterial Culture of Drainage Fluid for Predicting Surgical Site Infection After Crohn's Disease Surgery.

ABSTRACT:

Aim

Early detection of surgical site infection (SSI) allows for appropriate management after Crohn's disease (CD) surgery. The aim of this study was to evaluate the usefulness of bacterial culture of postoperative drainage fluid after CD surgery.

Methods

This study included 110 patients with CD who underwent surgery with bowel resection between January 2010 and March 2020 at Osaka University Hospital. Patients with only perianal surgery or incomplete records were excluded. Risk factors for SSI were evaluated in the context of clinical findings, including bacterial culture of postoperative drainage fluid, and bacterial species related to SSI were also examined.

Results

Of 110 patients, 18 (16.4%) developed SSI. Organ/space SSI developed in six, and a positive bacterial culture of drainage fluid (D-Posi) was found in five (83.3%). Of 104 patients without organ/space SSI, 31 (29.8%) were D-Posi (P = .027). Similarly, 68.8% with incisional SSI were D-Posi, whereas 26.6% without incisional SSI were D-Posi (P = .0021). Multivariate analysis revealed that D-Posi was an independent risk factor in both organ/space and incisional SSI. Bacterial examination showed that Pseudomonas aeruginosa and Enterococcus faecalis were significantly detected in patients with SSI.

Conclusion

This study suggests the usefulness of postoperative drainage fluid bacterial culture for early diagnosis of SSI after CD surgery.

SUBMITTER: Ichihara M

PROVIDER: S-EPMC9130903 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature

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Publications

Usefulness of Bacterial Culture of Drainage Fluid for Predicting Surgical Site Infection After Crohn's Disease Surgery.

Ichihara Momoko M Ogino Takayuki T Fujii Makoto M Haraguchi Naotsugu N Takahashi Hidekazu H Miyoshi Norikatsu N Uemura Mamoru M Doki Yuichiro Y Eguchi Hidetoshi H Mizushima Tsunekazu T

Annals of gastroenterological surgery 20211127 3

<h4>Aim</h4>Early detection of surgical site infection (SSI) allows for appropriate management after Crohn's disease (CD) surgery. The aim of this study was to evaluate the usefulness of bacterial culture of postoperative drainage fluid after CD surgery.<h4>Methods</h4>This study included 110 patients with CD who underwent surgery with bowel resection between January 2010 and March 2020 at Osaka University Hospital. Patients with only perianal surgery or incomplete records were excluded. Risk fa ...[more]

PMID: 35634186

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Project description:BackgroundProlonged external ventricular drainage (EVD) in patients with subarachnoid hemorrhage (SAH) leads to morbidity, whereas early removal can have untoward effects related to recurrent hydrocephalus. A metric to help determine the optimal time for EVD removal or ventriculoperitoneal shunt (VPS) placement would be beneficial in preventing the prolonged, unnecessary use of EVD. This study aimed to identify whether dynamics of cerebrospinal fluid (CSF) biometrics can temporally predict VPS dependency after SAH.MethodsThis was a retrospective analysis of a prospective, single-center, observational study of patients with aneurysmal SAH who required EVD placement for hydrocephalus. Patients were divided into VPS-dependent (VPS+) and non-VPS dependent groups. We measured the bicaudate index (BCI) on all available computed tomography scans and calculated the change over time (ΔBCI). We analyzed the relationship of ΔBCI with CSF output by using Pearson's correlation. A k-nearest neighbor model of the relationship between ΔBCI and CSF output was computed to classify VPS.ResultsFifty-eight patients met inclusion criteria. CSF output was significantly higher in the VPS+ group in the 7 days post EVD placement. There was a negative correlation between delta BCI and CSF output in the VPS+ group (negative delta BCI means ventricles become smaller) and a positive correlation in the VPS- group starting from days four to six after EVD placement (p < 0.05). A weighted k-nearest neighbor model for classification had a sensitivity of 0.75, a specificity of 0.70, and an area under the receiver operating characteristic curve of 0.80.ConclusionsThe correlation of ΔBCI and CSF output is a reliable intraindividual biometric for VPS dependency after SAH as early as days four to six after EVD placement. Our machine learning model leverages this relationship between ΔBCI and cumulative CSF output to predict VPS dependency. Early knowledge of VPS dependency could be studied to reduce EVD duration in many centers (intensive care unit length of stay).

Dataset Information

Usefulness of Bacterial Culture of Drainage Fluid for Predicting Surgical Site Infection After Crohn's Disease Surgery.

Aim

Methods

Results

Conclusion

Publications

Usefulness of Bacterial Culture of Drainage Fluid for Predicting Surgical Site Infection After Crohn's Disease Surgery.

Similar Datasets

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