Association Between Retinal Layer Thickness and Cognitive Decline in Older Adults.

ABSTRACT:

Importance

Retinal layer thickness is hypothesized to be related to cognitive function in patients with mild cognitive impairment (MCI) and Alzheimer disease (AD). However, longitudinal cohort studies of the healthy older population are scarce.

Objective

To investigate the association between retinal layer thickness and cognitive impairment and future cognitive decline in a community-based population cohort.

Design, setting, and participants

A total of 430 randomly sampled community-dwelling Korean individuals 60 years or older participated in the baseline assessment (mean [SD], 76.3 [6.6] years) 215 of whom completed a mean (SD) of 5.4 (0.6) years (range, 4.1-6.2 years) of follow-up. Using spectral-domain optical coherence tomography, the study team assessed the thic

SUBMITTER: Kim HM 

PROVIDER: S-EPMC9136677 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature