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Primary neuroendocrine carcinoma of the breast with paraneoplastic thrombocytosis; a rare case report.
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ABSTRACT: Introduction
primary neuroendocrine cancer of the breast (NECB) is a very rare entity, comprising less than 0,1% of all breast tumors. It was first reported in 1977 by cubilla et al.Case presentation
we report the case of a 60-year-old rural Syrian female who admitted to our hospital due to a painless lump in her right breast. Radiological & clinical findings were highly indicative of breast carcinoma. Therefore, a partial biopsy was performed and microscopic examination suggested the diagnosis of neuroendocrine carcinoma of the breast, which was confirmed by immunohistochemical staining. Lab findings were also indicative for anemia & thrombocytosis.Clinical discussion
neuroendocrine tumors are usually seen in the intestine & lungs. However, their presence as primary tumors in the breast is extremely rare.Conclusion
our article demonstrates a challenging case of primary neuroendocrine breast carcinoma with paraneoplastic thrombocytosis, which clarifies the major diagnostic & therapeutic approaches used in its management.
SUBMITTER: Kherbek H
PROVIDER: S-EPMC9142635 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature
Publications
Primary neuroendocrine carcinoma of the breast with paraneoplastic thrombocytosis; a rare case report.
Annals of medicine and surgery (2012) 20220422
<h4>Introduction</h4>primary neuroendocrine cancer of the breast (NECB) is a very rare entity, comprising less than 0,1% of all breast tumors. It was first reported in 1977 by cubilla et al.<h4>Case presentation</h4>we report the case of a 60-year-old rural Syrian female who admitted to our hospital due to a painless lump in her right breast. Radiological & clinical findings were highly indicative of breast carcinoma. Therefore, a partial biopsy was performed and microscopic examination suggeste ...[more]
