House Dust Mite Exposure through Human Milk and Dust: What Matters for Child Allergy Risk?

ABSTRACT: Allergies are major noncommunicable diseases associated with significant morbidity, reduced quality of life, and high healthcare costs. Despite decades of research, it is still unknown if early-life exposure to indoor allergens plays a role in the development of IgE-mediated allergy and asthma. The objective of this study is to contribute to the identification of early-life risk factors for developing allergy. We addressed whether two different sources of house dust mite Der p 1 allergen exposure during early life, i.e., human milk and dust, have different relationships with IgE levels and asthma outcomes in children. We performed longitudinal analyses in 249 mother-child pairs using data from the PIAMA birth cohort. Asthma symptoms and serum total and specific IgE levels in childre

SUBMITTER: Macchiaverni P 

PROVIDER: S-EPMC9143372 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature