Sex-Specific Difference in the Effect of Altitude on Sleep and Nocturnal Breathing in Young Healthy Volunteers.

ABSTRACT:

Importance

To date, there is no established evidence of sex-specific differences in altitude-induced sleep-disordered breathing (SDB) during polysomnography-confirmed sleep.

Objective

The aim of this study was to investigate whether differences in sex play a pivotal role in incidences of SDB and acute mountain sickness (AMS) when staying overnight at high altitude.

Design

This was a prospective cohort study.

Setting

Participants underwent overnight polysomnography (PSG) and clinical assessment in a sleep laboratory at 500 m and two consecutive days at 3270 m.

Participants

The participants comprised 28 (18 women) healthy, young, low-altitude residents with a median (interquartile range) age of 26.0 (25.0, 28.0) years.

Exposures

Altitude exposure.

SUBMITTER: Li T 

PROVIDER: S-EPMC9143383 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature