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Imine Palladacycles: Synthesis, Structural Analysis and Application in Suzuki-Miyaura Cross Coupling in Semi-Aqueous Media.

ABSTRACT: Treatment of the imines a-c with palladium(II) acetate in acetic acid yielded the μ-acetate dinuclear complexes 1a-c, which readily reacted with sodium chloride or bromide to provide μ-halide analogues. The reaction of the latter with nitrogen, phosphorus and oxygen donor nucleophiles yielded new imine palladacycles following the cleavage of the Pd₂X₂ unit. The complexes were fully characterized by microanalysis, ¹H, ¹³C and ³¹P NMR spectroscopies, as appropriate. The compounds were applied as catalysts in the Suzuki-Miyaura coupling reaction in aqueous and semi-aqueous media.

SUBMITTER: Bermudez-Puente B

PROVIDER: S-EPMC9144456 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature

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Imine Palladacycles: Synthesis, Structural Analysis and Application in Suzuki-Miyaura Cross Coupling in Semi-Aqueous Media.

Bermúdez-Puente Brais B Adrio Luis A LA Lucio-Martínez Fátima F Reigosa Francisco F Ortigueira Juan M JM Vila José M JM

Molecules (Basel, Switzerland) 20220514 10

Treatment of the imines a-c with palladium(II) acetate in acetic acid yielded the μ-acetate dinuclear complexes 1a-c, which readily reacted with sodium chloride or bromide to provide μ-halide analogues. The reaction of the latter with nitrogen, phosphorus and oxygen donor nucleophiles yielded new imine palladacycles following the cleavage of the Pd2X2 unit. The complexes were fully characterized by microanalysis, 1H, 13C and 31 ...[more]

PMID: 35630622

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